Join the team – PostDoc position available
We are offering a position for a PostDoc in cardiovascular epigenetics. In the planned project, we will study the interplay of transcription factors and epigenetic regulatory mechanisms in cardiovascular disease...
Epigenome and 3D chromatin structure of cardiac endothelial cells
Endothelial cells play crucial roles in physiology and are increasingly recognized as therapeutic targets in cardio-vascular disease. Here, we analyzed the regulatory landscape of cardiac endothelial cells by assessing chromatin...
2024 Joint Meeting of ESAC & ADMIRE Network
Registration and abstract submission for the 2024 Joint Meeting of ESAC and the ADMIRE network is now open: meeting.admire-network.org...
Molecular pharmacology of mineralocorticoid receptor antagonists
Mineralocorticoid receptor (MR) antagonists have shown remarkable benefits in the treatment of cardiovascular disease. However, their underutilization in clinical practice may be attributed to concerns regarding the risk of hyperkalemia...
Cell types of the heart: identities, interactions, and implications for cardiology
The heterocellular nature of the heart has been receiving increasing attention in recent years. In addition to cardiomyocytes as the prototypical cell type of the heart, non-myocytes such as endothelial...
Therapeutic targeting of mineralocorticoid receptors in pulmonary hypertension
Pulmonary hypertension (PH) is characterized by pulmonary vascular remodeling and associated with adverse outcomes. In patients with PH, plasma aldosterone levels are elevated, suggesting that aldosterone and its receptor, the...